The 1 and 3 Integrins Promote T Cell Receptor - mediated Cytotoxic T Lymphocyte Activation
نویسندگان
چکیده
Marie-Agnès Doucey, Daniel F. Legler, Mustapha Faroudi, Nicole Boucheron, Petra Baumgaertner, Dieter Naeher, Marek Cebecauer, Denis Hudrisier, Curzio Rüegg, Ed Palmer, Salvatore Valitutti, Claude Bron, and Immanuel F. Luescher From the Institute for Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland, the Ludwig Institute for Cancer Research, Lausanne Branch, University of Lausanne, 1066 Epalinges, Switzerland, INSERM U563, CHU Purpan, 31059 Toulouse, France, the Kantonsspital, University of Basel, 4031 Basel, Switzerland, and the Centre Pluridisciplinaire d’Oncologie, University of Lausanne Medical School, 1066 Epalinges, Switzerland
منابع مشابه
Contribution of lymphocyte function-associated-1/intercellular adhesion molecule-1 binding to the adhesion/signaling cascade of cytotoxic T lymphocyte activation
A rapid induction of adhesion to immobilized intercellular adhesion molecule (ICAM)-1 occurs when cytotoxic T lymphocytes (CTL) are stimulated with either soluble anti-T cell receptor (TCR) monoclonal antibodies (mAb) or with immobilized alloantigen, and this binding is blocked by the addition of anti-lymphocyte function-associated (LFA)-1 mAbs. Requirements for activating LFA-1 adhesion to ICA...
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